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Glossary

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
A Agonist A drug capable of combining with receptors to initiate drug actions

Amino acid Building block of peptides/proteins

Analogue Similar in chemical and physical structure

B    

C    

D Deslorelin Peptide analogue of GnRH

DNA Short for deoxyribonucleic acid, a molecule that encodes operating instructions for our bodies

E    

F FDA The Food and Drug Administration, the U.S. government pharmaceuticals regulatory body

FSH Follicle-Stimulating Hormone

G GnRH Gonadotropin-Releasing Hormone

Gonadotropin Hormone capable of promoting gonadal growth and function

H hCG human Chorionic Gonadotropic hormone

Hormone Proteins that are chemical messengers in the body

I Immunogenic Having properties of an antigen i.e. able to stimulate an immune response

Immunoglobulin An antibody protein. There are five different types, known as IgG, IgA, IgD, IgM and IgE. The immunoglobulin used in both Enbrel and Remicade is IgG

Immunosuppressant A drug that suppresses the natural functioning of the immune system, used mainly to reduce the chance of rejection of a transplanted organ

J


K    

L Lead A treatment idea that has shown enough promise to warrant being followed up some more

LH Luteinizing hormone

M    

N National Phase The taking of a PCT Application to an individual patent office Notice of Allowance Advice from the U.S. Patent Office of that Office's intention to grant a patent

NRA National Regulatory Authority (Australia)

O Oestrous Period of maximal readiness for reproduction of female animals

P PCT Application An application for a patent under the rules of the Patent Cooperation Treaty; that patent provides the 'common platform', from which applications for patents can be made to the individual national patent offices

Peptide Two or more amino acids linked by chemical bonds

Phase One of several trials a drug makes on the road to being approved. Broadly speaking Phase I is designed to test if the drug is safe, Phase II if it is efficacious in a small sample and Phase III if it is efficacious in a large sample

Pipeline The drug candidates a company has in its portfolio at various stages of clinical or pre-clinical work
Placebo
An inert substance given as a medicine during clinical trials for its suggestive effect

Platform A collection of technologies that speeds the task of drug research

Polypeptide A chain of peptides

Priority Date The date on which a provisional application for a patent was first filed

Prostaglandins Hormones involved in reproduction, inflammation and other body processes

Protein A class of fairly common molecules in the human body that includes antibodies hormones and enzymes

Q


R Recombinant DNA DNA that has been cut and spliced in order to alter the genetic code (introduce a gene(s) that codes for a protein not normally found in the organism)

S Subcutaneous Beneath the skin

T Target A disease, or cause of a disease that a drug development team is aiming to develop treatments for.

TGA Therapeutic Goods Authority (Australia)

U


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X


Y


Z