Ovuplant®

Trial Data/Field Results:

Prediction of Cycle Length Based on Observations in USA & Australia

For a stud with 200 mares and a 70% 1st cycle conception rate, only 60 mares will need to be re-serviced (See diagram below)
Small increase in "unusual" cycles

Note that 9/200 (4.5%) of mares will have "unusual" cycles after Ovuplant^®

For no agent this number is 7/200 (3.5%) - only a 1% difference

Prediction of Cycle Length Based on Observations in USA & Australia


Cycle Length	Predicted Number of Mares
	Ovuplant^®	No Agent
< 25	51	53
26 - 30	6	4
> 30	3	3
Total	60	60

Australian Data:

Data generated from records of 3 studs under the care of Dr Angus McKinnon (~4500 cycles) - Analysis of data by Peptech scientists (See figures below)

Figures:

Comparison of average cycle length over the entire study shows an increase of 1.2 days after using Ovuplant®

Breakdown of data by stud and cycle number

	No. of Cycles	No. 1st Cycles	No. 2nd Cycles	No. 3rd Cycles	No. 4th Cycles	Ovuplant^®	hCG	No Agent
Stud 1 1992-98	344	263	64	15	2	69	218	57
Stud 2 1992-98	193	152	33	8	-	47	113	33
Stud 3 1996-99	358	251	85	18	4	117	179	62
TOTAL	895	666	183	41	6	233	510	152

Chart shows a small increase in 1st cycle length using Ovuplant^®

	No. of Cycles	Average Cycle Length	Long Cycles
		Days	26 - 30 Days	> 30 Days
Ovuplant^®	233	22.8	10.7	4.3
hCG	510	21.6	7.0	4.5
No Agent	152	21.7	9.2	3.9
TOTAL	895	21.9	8.3	4.3

USA Data:

Data generated from four USA Farms (Kentucky & Florida Thoroughbreds; Texas Quarter horse and Maryland Standard bred). Ovuplant^® does not increase the percentage of mares with >30 day cycles - there is a modest increase in the 26-30 day group (see figure below).

Kentucky:

	No. of Cycles	Average Cycle Length (d)	26 - 30d Cycle (%)	> 30d Cycle (%)
Ovuplant^®	78	24.7	20.5	11.5
Non-Ovuplant	43	24.8	13.6	15.6